DNA/RNA Methylation
Bisulfite Conversion Kits
All bisulfite conversion kits are available in spin-column, 96-well, and MagBead formats. These innovative bisulfite conversion kits feature streamlined workflows, ≥ 99% conversion rates, automation friendly options, and low elution volumes for concentrated, bisulfite-converted DNA.
All MagBead kits are automation ready! Scripts available, contact automation@zymoresearch.com
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EZ DNA Methylation-Lightning
(CE-IVD) |
EZ DNA Methylation-Direct | EZ DNA Methylation-Gold | EZ DNA Methylation |
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Rapid workflow, most gentle chemistry | Use directly with cells and tissues | Classic bisulfite conversion | Classic bisulfite conversion | |
Which kit is right for me? | Best for new users and Illumina Array users | Best for working with cells/tissue as direct input, and validated third party kits* | Best for legacy users and users working with validated third-party kits** | Best for legacy users and Illumina Array users |
Conversion Efficiency | > 99.5% | > 99.5% | > 99% | > 99% |
Input | 100 pg – 2 µg of DNA | DNA (≥ 50 pg), cells (≥ 10), blood, tissue, FFPE | 500 pg – 2 µg of DNA | 500 pg – 2 µg of DNA |
Processing Time | 1.5 hr | 4 hr | 3 hr | 12-16 hr |
Validated For | Illumina MethylationEPIC Array (MagBead format) | *Accel-NGS Adaptase for Single Cell Methyl-Seq | **Agilent SureSelect MethylSeq, IDT xGen™ Methylation-Sequencing | Illumina MethylationEPIC Array (All formats) |