Plasmid Purification Kits

Simple, fast plasmid purification kits at an affordable price. Get the highest DNA yields possible in minutes with our collection of unrivaled plasmid purification kits.

Need help finding the right plasmid purification kit? Click here to compare kits.

Plasmid Purification Kit Comparison Tables

Zymo Research offers a variety of plasmid purification kits in different scales and formats that are highly efficient and simple to use. All our plasmid purification kits recover transfection-grade plasmid DNA that is suitable for the most sensitive molecular biology techniques, such as restriction digestion, PCR, sequencing and cloning. Use the tables below to find the right plasmid purification kit for you. If you are unsure about your plasmid DNA needs, then the ZymoPURE Miniprep Kit is a good starting point because of its versatility.

Miniprep Plasmid Purification Kits

Kit	Direct Lysis^†	Desired Processing Volume	Desired Plasmid Yield	Desired Plasmid Concentration	Desired Endotoxin Levels (EU/µg plasmid)	Plasmid Size	Processing Time
ZymoPURE Miniprep	No	1 — 5 ml	1 — 100 µg	500 — 1,000 ng/µl	≤ 1 EU/µg	≤ 200 kb	15 min
ZymoPURE 96 Plasmid Miniprep Kit	No	1 — 5 ml	1 — 100 µg	100 — 1,000 ng/µl	≤ 1 EU/µg	≤ 200 kb	60 min
ZR Plasmid Miniprep - Classic	No	1 — 5 ml	< 20 µg	100 — 500 ng/µl	≤ 50 EU/µg	≤ 25 kb	15 min
Zyppy Plasmid Miniprep Kit	Yes	< 1 ml	1 — 3 µg	≤ 100 ng/µl	≤ 50 EU/µg	≤ 25 kb	8 min
Zyppy-96 Plasmid Kit	Yes	< 1 ml	1 — 3µg	≤ 100 ng/µl	≤ 50 EU/µg	≤ 25 kb	45 min
Zyppy-96 Plasmid MagBead Miniprep	Yes	< 1 ml	1 — 3 µg	≤ 100 ng/µl	≤ 50 EU/µg	≤ 25 kb	45 min
ZR BAC DNA Miniprep	No	1 — 5 ml	1 µg	≤ 50 ng/µl	≤ 50 EU/µg	≤ 200 kb	15 min
_{^†Direct lysis allows you to omit traditional cell pelleting and resuspension steps by lysing the cells directly in the overnight culture media.}

Midi, Maxi & Giga Prep Plasmid Purification Kits (Large Scale)

Kit	Direct Lysis^†	Desired Processing Volume	Desired Plasmid Yield	Desired Plasmid Concentration	Desired Endotoxin Levels (EU/µg plasmid)	Plasmid Size	Processing Time
ZymoPURE Express Midiprep	Yes	25 ml	100 — 200 µg	0.5 — 1 µg/µl	≤ 1 EU/µg	≤ 200 kb	15 min
ZymoPURE II Plasmid Midiprep	No	≤ 50 ml	200 — 400 µg	≥ 1 µg/µl	≤ 0.025 EU/µg	≤ 200 kb	18 min
ZymoPURE II Plasmid Maxiprep	No	≤ 150 ml	600 — 1,200 µg	≥ 1 µg/µl	≤ 0.025 EU/µg	≤ 200 kb	< 18 min
ZymoPURE II Plasmid Gigaprep	No	1 — 2.5 L	3,000 — 20,000 µg	≥ 1 µg/µl	≤ 0.025 EU/µg	≤ 200 kb	< 45 min
_{^†Direct lysis allows you to omit traditional cell pelleting and resuspension steps by lysing the cells directly in the overnight culture media.}

Plasmid Purification Kits Overview

Plasmid DNA purification is a cornerstone of many molecular biology and biochemistry labs. Furthermore, it is used extensively prior to a variety of applications. Some of these applications are transfection, bacterial transformation, restriction endonuclease digestion, PCR, sequencing, and in vitro transcription.

Good plasmid purification kits can robustly isolate high quality, endotoxin-free plasmid DNA. The best kits do this fast and utilize a simple protocol. Of course, fast and simple plasmid purification kits are indispensable tools in every researcher’s arsenal.

Zymo Research provides unrivaled plasmid DNA purification kits at an affordable price. Thus, every lab can be equipped with the essentials. Several formats are available for isolating bacterial plasmids, yeast plasmids, or BAC, YAC, & PAC DNA. High-quality plasmids isolated using Zymo's technology can be eluted directly from the column in water. Above all, the ultra-pure DNA is ready for all sensitive downstream applications.

Plasmid Purification Kits

DNA

RNA

DNA/RNA Co-Extraction

Epigenetics

Microbiomics

Sample Collection

NGS Library Prep Kits

E. coli

Yeast

Protein & Enzymes

Columns & Plastics

Devices & Instruments

Plasmid Purification Kit Comparison Tables

Plasmid Purification Kits Overview