The Genomic DNA Clean & Concentrator kits are DNA clean up kits that provide quick (5 minute) recovery of ultra-pure, high molecular weight DNA (e.g., genomic, mitochondrial, plasmid (BAC/PAC), viral, phage, whole genome amplified DNA, etc.) from any enzymatic reaction or impure preparation (e.g., Proteinase K digestion). With these high molecular weight DNA clean up kits, there is no need for organic denaturants, chloroform, or messy precipitations. Simply add the specially formulated DNA Binding Buffer to the sample and purify the DNA using the supplied Zymo-Spin column or 96-well plate. For those looking for an automated solution, the DNA Clean & Concentrator MagBead Kit can be easily carried out using liquid handlers or magnetic bead movers for high-throughput clean up and concentration of high molecular weight DNA. The recovered DNA from these clean up kits is suitable for next generation sequencing, PCR, endonuclease digestion, and other enzymatic procedures. These high molecular weight DNA clean up kits are also compatible with smaller DNAs (50 bp to 10 kb) from PCR, digestions, crude plasmid preparations, cDNA synthesis, etc.